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Hemarthrosis revealing congenital factor XI deficiency

Authors :
Neila Ben Romdhane
Nihel Meddeb
H. Ajlani
Leila Souabni
S. Sellami
Source :
Joint bone spine. 75(3)
Publication Year :
2007

Abstract

Congenital factor XI deficiency (also known as the Rosenthal syndrome or hemophilia C) manifests as minor bleeding, usually after trauma or surgery. We report a case in which bilateral knee hemarthrosis was the first manifestation. The patient presented at 32 years of age with a 2-year history of mechanical pain and intermittent swelling in both knees. Knee aspiration recovered blood-tinged fluid. The laboratory workup showed severe factor XI deficiency. Replacement therapy with fresh frozen plasma was effective. Tests in the family showed factor XI deficiency in the patient's sister.

Details

ISSN :
17787254
Volume :
75
Issue :
3
Database :
OpenAIRE
Journal :
Joint bone spine
Accession number :
edsair.doi.dedup.....0c339752fe1c92f5c92e3ded5036040d