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Prenatal epidemiology of pediatric tumors
- Source :
- Current oncology reports. 2(3)
- Publication Year :
- 2000
-
Abstract
- With the exception of a small percentage of cases attributable to hereditary cancer syndromes (eg, familial retinoblastoma) or genetic syndromes (Down syndrome), the etiology of most childhood cancers is unknown. Recent epidemiologic studies have focused on the prenatal period and have investigated potential associations with parental age, cigarette smoking, birth weight of the child, parental occupational exposures, and specific environmental exposures. The following challenges lie ahead for future epidemiologic studies of childhood cancer: 1) improvement of diagnostic classification; 2) improved methods for exposure assessment; 3) evaluation of data from molecular biology to generate biologically derived hypotheses; and 4) incorporation of markers of genetic susceptibility when feasible.
- Subjects :
- Male
medicine.medical_specialty
Down syndrome
Pediatrics
Adolescent
Birth weight
Prenatal diagnosis
Risk Assessment
Age Distribution
Electromagnetic Fields
Pregnancy
Risk Factors
Neoplasms
Prenatal Diagnosis
Epidemiology
medicine
Genetic predisposition
Humans
Sex Distribution
Child
Radiation
business.industry
Smoking
Infant
Environmental exposure
Environmental Exposure
medicine.disease
United States
Oncology
Child, Preschool
Prenatal Exposure Delayed Effects
Etiology
Carcinogens
Female
business
Subjects
Details
- ISSN :
- 15233790
- Volume :
- 2
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Current oncology reports
- Accession number :
- edsair.doi.dedup.....0c2b75f0fdec47314e0aaf547746b606