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Influence of biopsy cores number performed with targeted prostate biopsy on the likelihood of a positive result in patients with clinically significant prostate cancer
- Source :
- Onkourologiâ, Vol 16, Iss 3, Pp 62-69 (2020), Onkourologiya
- Publication Year :
- 2020
- Publisher :
- Publishing House ABV Press, 2020.
-
Abstract
- Background. Targeted biopsy is proposed as a method of choice in the algorithm of prostate cancer diagnosis, but not all the features of method has been evaluated.Objective: determine the rational number of targeted biopsy samples in patients with clinically significant prostate cancer.Materials and methods. The magnetic resonance imaging and fusion biopsy data of 156 patients with suspected prostate cancer were retrospectively evaluated.Results and conclusion. In the study statistically significant dependence of the positive histological results in patients with clinically significant prostate cancer from the number of biopsy samples was found. The potential probability of a false negative histological examination with an insufficient number of biopsy samples was noted. These results confirm the latest published data of potential targeted biopsy false in true positive patients after multiparametric magnetic resonance imaging. An increase in the number of biopsy samples in the target lesion reduces the likelihood of false-negative results. The main causes of such discrepancy are some technical laxity and the heterogeneous histological structure of prostate cancer. Increase the number of biopsy cores can reduce the likelihood of false-negative results.
- Subjects :
- Target lesion
medicine.medical_specialty
Urology
030232 urology & nephrology
MAJOR CLINICAL STUDY
PROSTATE CANCER
Targeted biopsy
03 medical and health sciences
Prostate cancer
0302 clinical medicine
RETROSPECTIVE STUDY
Biopsy
CANCER PATIENT
medicine
TARGETED BIOPSY
Radiology, Nuclear Medicine and imaging
ARTICLE
Multiparametric Magnetic Resonance Imaging
Fusion Biopsy
Histological examination
MALE
medicine.diagnostic_test
business.industry
HUMAN
Magnetic resonance imaging
HISTOPATHOLOGY
STATISTICALLY SIGNIFICANT RESULT
prostate cancer
multiparametric magnetic resonance imaging
medicine.disease
MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING
PROBABILITY
Oncology
HUMAN TISSUE
Nephrology
030220 oncology & carcinogenesis
targeted biopsy
Medicine
Surgery
Radiology
PROSTATE BIOPSY
business
FALSE NEGATIVE RESULT
Subjects
Details
- ISSN :
- 19961812 and 17269776
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Cancer Urology
- Accession number :
- edsair.doi.dedup.....0c23f957b095900a65c6099141b6e8a6