Back to Search Start Over

InterMOD: integrated data and tools for the unification of model organism research

Authors :
Richard N. Smith
Pushkala Jayaraman
Rama Balakrishnan
Elizabeth A. Worthey
Steven B. Neuhauser
Gail Binkley
Julie Sullivan
Lincoln Stein
J. D. Wong
Jelena Aleksic
Sierra A. T. Moxon
J. Michael Cherry
Monte Westerfield
Todd W. Harris
Quang M. Trinh
Rachel Lyne
Benjamin C. Hitz
Gos Micklem
Simon N. Twigger
Andrew Vallejos
Howie Motenko
Joel Richardson
Christian Pich
Kalpana Karra
Source :
Scientific Reports
Publication Year :
2013
Publisher :
Nature Publishing Group, 2013.

Abstract

Model organisms are widely used for understanding basic biology and have significantly contributed to the study of human disease. In recent years, genomic analysis has provided extensive evidence of widespread conservation of gene sequence and function amongst eukaryotes, allowing insights from model organisms to help decipher gene function in a wider range of species. The InterMOD consortium is developing an infrastructure based around the InterMine data warehouse system to integrate genomic and functional data from a number of key model organisms, leading the way to improved cross-species research. So far including budding yeast, nematode worm, fruit fly, zebrafish, rat and mouse, the project has set up data warehouses, synchronized data models and created analysis tools and links between data from different species. The project unites a number of major model organism databases, improving both the consistency and accessibility of comparative research, to the benefit of the wider scientific community.

Details

Language :
English
ISSN :
20452322
Volume :
3
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....0bf694e34938d79d154812dc240cd0d1