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Flat detector C-arm CT-guided transthoracic needle biopsy of small (≤2.0 cm) pulmonary nodules: diagnostic accuracy and complication in 100 patients
- Source :
- La radiologia medica. 121:268-278
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- This study aimed at assessing the usefulness of flat detector cone-beam CT virtual navigation-guided transthoracic needle biopsy of small (≤2.0 cm) pulmonary nodules in terms of diagnostic accuracy and complications to evaluate the diagnostic performance and complications of small pulmonary nodules under cone-beam CT (CBCT) guidance. A total of 100 patients with 100 solid lung nodules were retrospectively enrolled to undergo transthoracic needle biopsy (TNB) procedures. The mean diameter of lesions was 1.25 cm ± 0.39 (range 0.50–2.00 cm). The needle path was carefully planned and calculated on the CBCT virtual navigation guidance system, which acquired 3D CT-like cross-sectional images. Diagnostic performance, complication rate, and patient radiation exposure were investigated. The technical success rate of TNB under iGuide CBCT virtual navigation system was 99 % (99/100). The sensitivity, specificity, and accuracy of TNB of small nodules under iGuide CBCT virtual navigation guidance were 98.7 % (77/78), 90.5 % (19/21), and 97.0 % (96/99), respectively. The number of pleural passages with coaxial needle, biopsies, and CBCT acquisitions were 1.09 ± 0.32, 1.20 ± 0.47, and 3.06 ± 1.35, respectively. Complications occurred in 22 (22 %) cases. The mean total procedure time was 12.84 min ± 3.74, resulting in a mean exposure dose of 7.6 mSv ±3.1. Flat detector Cone-beam CT-guided TNB is a highly accurate and safe diagnostic method for small (≤2.0 cm) lung nodule.
- Subjects :
- Adult
Image-Guided Biopsy
Male
medicine.medical_specialty
Lung Neoplasms
030218 nuclear medicine & medical imaging
Young Adult
03 medical and health sciences
0302 clinical medicine
Biopsy
medicine
Humans
Radiology, Nuclear Medicine and imaging
Aged
Retrospective Studies
Neuroradiology
Aged, 80 and over
Multiple Pulmonary Nodules
medicine.diagnostic_test
business.industry
Biopsy, Needle
Ultrasound
Interventional radiology
Nodule (medicine)
General Medicine
Middle Aged
030220 oncology & carcinogenesis
Female
Radiology
medicine.symptom
Tomography, X-Ray Computed
business
Complication
Subjects
Details
- ISSN :
- 18266983 and 00338362
- Volume :
- 121
- Database :
- OpenAIRE
- Journal :
- La radiologia medica
- Accession number :
- edsair.doi.dedup.....0bec761dc621f0a08b8e11f284600d41
- Full Text :
- https://doi.org/10.1007/s11547-015-0604-3