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Can Combined Screening of Ultrasound and Elastography Improve Breast Cancer Identification Compared with MRI in Women with Dense Breasts-a Multicenter Prospective Study

Authors :
Wen Xu
Hong-Yuan Xue
Pintong Huang
Yang Gu
Weiwei Zhan
Qi Zhou
Xiaoyan Xie
Luying Gao
Ping Zhou
En-Sheng Xue
Yuxin Jiang
Bao-Ming Luo
Wu Chen
Hong-Yu Ding
Chun-Quan Zhang
Cai Chang
Qing Zhou
Jia-Wei Tian
Zhong-Ping Mu
Yu-Ming Mu
Hongyan Wang
Jian-Feng Guo
Li Liu
Ying Gu
Hong-Qiao Wang
Jian-Jun Yuan
Li-Xue Yin
Jin-Feng Xu
Chun-Song Kang
You-Bin Deng
Yu-Hong Zhang
Jie Li
Jianchu Li
Wei-Dong Ren
Hui Wang
Man Chen
Haitao Ran
Tong Jiao
Jie-Ying Zhang
Xiang-Xiang Jing
Sheng-Lan Guo
Source :
Journal of Cancer
Publication Year :
2020
Publisher :
Ivyspring International Publisher, 2020.

Abstract

Objectives: To assess the performance of elastography (ES) and ultrasound (US) in predicting the malignancy of breast lesions and to compare their combined diagnostic value with that of magnetic resonance imaging (MRI). Materials and Methods: The study prospectively enrolled 242 female patients with dense breasts treated in 35 heath care facilities in China between November 2018 and October 2019. Based on conventional US and elastography, radiologists classified the degree of suspicion of breast lesions according to the US Breast Imaging Reporting and Data System (BI-RADS) criteria. The diagnostic value was compared between US BI-RADS and MRI BI-RADS, with pathological results used as the reference standard. Results: The results demonstrated that irregular tumor shape, a nonparallel growth orientation, indistinct margins, angular contours, microcalcifications, color Doppler flow and ES score on US imaging were significantly related to breast cancer in dense breasts (P=0.001; P=0.001; P=0.008; P

Details

Language :
English
ISSN :
18379664
Volume :
11
Issue :
13
Database :
OpenAIRE
Journal :
Journal of Cancer
Accession number :
edsair.doi.dedup.....0bba224f557a56f416f924b54604ace2