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Expression of common acute lymphoblastic leukaemia antigen and terminal deoxynucleotidyl transferase in normal mononuclear blood cells during diffusion chamber culture
- Source :
- Scandinavian journal of haematology. 27(1)
- Publication Year :
- 1981
-
Abstract
- Peripheral mononuclear blood cells of 2 healthy individuals were cultured over a 13 d period in diffusion chambers. A high percentage of cALL antigen positive cells and later on TdT containing cells appeared during culture. The cALL+ cells could be clearly distinguished into 2 groups: a population with weak and diffuse fluorescence and a small number of ring-like brightly dyed cells. The first group develops into TdT+ cells and therefore resembles immature T-cells. The interpretation of the ring-like stained cells is still preliminary, but it cannot be excluded, that these cells represent a cell population with more than lymphatic differentiation capacity.
- Subjects :
- Diffusion chamber
Pathology
medicine.medical_specialty
education.field_of_study
Cell
Population
Fluorescent Antibody Technique
Cell Differentiation
Hematology
Biology
Leukemia, Lymphoid
medicine.anatomical_structure
Lymphatic system
Antigen
Terminal deoxynucleotidyl transferase
Antigens, Neoplasm
DNA Nucleotidylexotransferase
DNA Nucleotidyltransferases
medicine
Humans
Lymphocytes
CD5
education
Common acute lymphoblastic leukaemia antigen
Cells, Cultured
Subjects
Details
- ISSN :
- 0036553X
- Volume :
- 27
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scandinavian journal of haematology
- Accession number :
- edsair.doi.dedup.....0b9f6fff271495d269f93b2caa2a1c0f