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Evaluation of genetic damage in pesticides applicators from the province of Córdoba, Argentina
- Source :
- Environmental Science and Pollution Research. 26:20981-20988
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- The impact evaluation of pesticide exposure is conducted using combined data from biomonitoring and environmental monitoring. Damage to the human genome is, probably, the leading cause of chronic-degenerative disorders, reproductive toxicology, and developmental problems. Although the general population is exposed to pesticides, workers in the agrochemical industry and farmers represent a high-risk group due to the occupational and environmental exposure. The aim of this study is to determine whether occupational exposure to agrochemicals in Córdoba (Argentina) constitute a factor of genotoxic damage. The study was conducted in 30 pesticide applicators from the province of Córdoba. Chromosomal aberrations (CAs), micronuclei (MN), and comet assays (CO) were performed. The current study shows that occupational exposure to pesticides increases values of CAs, MN, and DNA fragmentation biomarkers, all indicators of damage to the genetic material. Evidence suggests that chronic exposure to pesticides is a potential risk to workers health.
- Subjects :
- Adult
Male
Agrochemical
Health, Toxicology and Mutagenesis
Population
Argentina
010501 environmental sciences
Biology
medicine.disease_cause
01 natural sciences
Occupational Exposure
Environmental health
Biomonitoring
medicine
Cholinesterases
Humans
Environmental Chemistry
Ecotoxicology
Pesticides
education
0105 earth and related environmental sciences
Chromosome Aberrations
education.field_of_study
business.industry
General Medicine
Environmental exposure
Pesticide
Pollution
Agricultural Workers' Diseases
Micronucleus test
business
Biomarkers
Genotoxicity
DNA Damage
Environmental Monitoring
Subjects
Details
- ISSN :
- 16147499 and 09441344
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Environmental Science and Pollution Research
- Accession number :
- edsair.doi.dedup.....0b7fba95bc838b0e1dd46c1b2b3c9ab3