Two new triterpene saponins from the aerial parts of Paraquilegia microphylla

Two new triterpene saponins, paraquinosides A (1) and B (2) were isolated from the aerial parts of Paraquilegia microphylla (Royle) Dromm. et Hutch, a Tibetan ethnic medicine distributed in the Qinghai-Tibet Plateau. On the basis of 10 and 20 NMR evidence, their structure was elucidated as 3-O-alpha-L-rhamnopyranosyl (1 -> 2)-beta-D-glucopyranosyl-15-dehydroxyl-16-O-methyl-24, 25-deoxy-26-hydroxylshengmanol-26-O-beta-D-glucopyranoside (1) and 3-O-alpha-L-Rhamnopyranosyl (1 -> 2)-[beta-D-glucopyranosyl(1 -> 3)]-beta-D-glucopyranosyl-15-dehydroxyl-16-O-methyl-24, 25-deoxy-26-hydroxylshengmanol-26-O-beta-D-glucopyranoside (2), respectively. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.