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Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes
- Source :
- Diabetes, obesitymetabolism. 17(2)
- Publication Year :
- 2014
-
Abstract
- We determined the effects of exercise on pancreatic endocrine responses to metabolic stimuli in subjects with type 2 diabetes (T2D) and examined the influence of subjects' diabetic status. Fourteen subjects underwent a hyperglycaemic clamp with glucagon-like peptide-1 (GLP-1) infusion and arginine injection, the morning after a 1-h walk or no exercise. Subjects were stratified by high and low fasting plasma glucose (FPG) levels and by glycated haemoglobin (HbA1c) levels, as well as by current use/non-use of antidiabetic medication. In the entire cohort, exercise did not alter insulin secretion, while glucagon levels were increased in all clamp phases (p
- Subjects :
- Blood Glucose
Male
medicine.medical_specialty
endocrine system diseases
Arginine
Endocrinology, Diabetes and Metabolism
Type 2 diabetes
Glucagon
Injections
Endocrinology
Glucagon-Like Peptide 1
Internal medicine
Insulin Secretion
Internal Medicine
medicine
Endocrine system
Humans
Insulin
Insulin secretion
Infusions, Intravenous
Exercise
Pancreas
Morning
business.industry
Fasting
medicine.disease
Clamp
Treatment Outcome
Diabetes Mellitus, Type 2
Hyperglycemia
Cohort
Glucose Clamp Technique
Female
business
Subjects
Details
- ISSN :
- 14631326
- Volume :
- 17
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Diabetes, obesitymetabolism
- Accession number :
- edsair.doi.dedup.....0b1a3ce48a290fef9c3d516bab5ab6a2