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In Search of Geographical Patterns in European Mitochondrial DNA
- Source :
- The American Journal of Human Genetics. 71(5):1168-1174
- Publication Year :
- 2002
- Publisher :
- Elsevier BV, 2002.
-
Abstract
- Previous studies of mitochondrial DNA (mtDNA) in Europe and the Near East have suggested that, in contrast with classical markers and the Y chromosome, mtDNA does not exhibit significant geographical structuring. Here, we show that, with a sufficiently large sample size and a better resolved mtDNA tree, clades of mtDNA do indeed exhibit gradients similar to those of other marker systems. However, the more detailed analyses afforded by molecular sequence data suggest that the explanations for these gradients are likely to be much more complex than those proposed for classical markers.
- Subjects :
- Mitochondrial DNA
Population genetics
Biology
Y chromosome
DNA, Mitochondrial
Evolution, Molecular
03 medical and health sciences
chemistry.chemical_compound
Report
Genetic variation
Genetics
Humans
Genetics(clinical)
Clade
Genetics (clinical)
030304 developmental biology
0303 health sciences
Principal Component Analysis
Chromosomes, Human, Y
030305 genetics & heredity
Genetic Variation
Large sample
Europe
chemistry
Molecular sequence
DNA
Subjects
Details
- ISSN :
- 00029297
- Volume :
- 71
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- The American Journal of Human Genetics
- Accession number :
- edsair.doi.dedup.....0add7b2e45edf58fff2b6b9ec5560c7f
- Full Text :
- https://doi.org/10.1086/342930