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Distinctive immunoregulatory effects of adenosine on T cells of older humans
- Source :
- The FASEB Journal. 26:1301-1310
- Publication Year :
- 2011
- Publisher :
- Wiley, 2011.
-
Abstract
- A role for adenosine in immunosenescence was investigated in T cells from older (≥65 yr) and younger (24–45 yr) healthy humans. Adenosine concentrations in cultures of activated T cells were significantly higher (P
- Subjects :
- Adult
Male
medicine.medical_specialty
Adenosine
Adenosine A2 Receptor Agonists
T-Lymphocytes
Endogeny
Biology
Biochemistry
Research Communications
Young Adult
CD28 Antigens
Antigens, CD
Internal medicine
Phenethylamines
Genetics
medicine
Humans
Cytotoxic T cell
Molecular Biology
Cells, Cultured
Aged
Aged, 80 and over
Dose-Response Relationship, Drug
Apyrase
Adenine
Chemotaxis
Age Factors
CD28
Immunosenescence
Middle Aged
Triazoles
Flow Cytometry
Adenosine receptor
Adenosine A2 Receptor Antagonists
Pyrimidines
Endocrinology
Cytokines
Female
Biotechnology
medicine.drug
Subjects
Details
- ISSN :
- 15306860 and 08926638
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- The FASEB Journal
- Accession number :
- edsair.doi.dedup.....0adaa1d9cb35bf5fdd786f1572e814f0