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Simultaneous resection of pancreas and liver metastases from different metachronous primary cancers
- Source :
- Journal of hepato-biliary-pancreatic surgery. 8(5)
- Publication Year :
- 2001
-
Abstract
- Resection of a pancreatic head tumor and partial resection of the liver for metastatic lesions were carried out simultaneously in a 72-year-old woman. The patient had a history of two previous operations, right nephrectomy for renal cell carcinoma (clear cell type), done 14 years previously, and an Autincloss procedure for cancer of the left breast (solid tubular carcinoma); (T1N0M0; stage I) done 7 years previously. At the current presentation, preoperative radiographic examination showed a hypervascular tumor in each of the pancreatic and hepatic lesions, but with different patterns. On the basis of histological findings in the two resected specimens, it was difficult to establish whether the hepatic tumor originated from the renal cell carcinoma or the breast cancer, but postoperative immunohistochemical studies for carcinoembryonic antigen (CEA), estrogen receptors, and gross cystic disease fluid protein (GCDFP)-15 showed that the pancreatic tumor had metastasized from the renal cell carcinoma, and the liver tumor from the breast cancer. The immunohistochemical investigation of different markers thus proved to be useful in making the final diagnosis of metastatic lesions from different and metachronous cancers.
- Subjects :
- CA15-3
Pathology
medicine.medical_specialty
Liver tumor
CA 15-3
Breast Neoplasms
Breast cancer
Carcinoembryonic antigen
Pancreatic tumor
Renal cell carcinoma
Medicine
Humans
Carcinoma, Renal Cell
Aged
Hepatology
biology
business.industry
Liver Neoplasms
Cancer
medicine.disease
Immunohistochemistry
Kidney Neoplasms
Pancreatic Neoplasms
biology.protein
Surgery
Female
business
Subjects
Details
- ISSN :
- 09441166
- Volume :
- 8
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of hepato-biliary-pancreatic surgery
- Accession number :
- edsair.doi.dedup.....0a7e1211e735d126e77fb640b78fcead