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Simultaneous resection of pancreas and liver metastases from different metachronous primary cancers

Authors :
Yoshiyasu Terashima
Yoh Fukuta
Toshiharu Maeda
Masamitsu Harada
Seiki Tashiro
Kouichi Ikawa
Toshinobu Matsumura
Hisanori Uehara
Akiko Hino
Masafumi Horiuchi
Source :
Journal of hepato-biliary-pancreatic surgery. 8(5)
Publication Year :
2001

Abstract

Resection of a pancreatic head tumor and partial resection of the liver for metastatic lesions were carried out simultaneously in a 72-year-old woman. The patient had a history of two previous operations, right nephrectomy for renal cell carcinoma (clear cell type), done 14 years previously, and an Autincloss procedure for cancer of the left breast (solid tubular carcinoma); (T1N0M0; stage I) done 7 years previously. At the current presentation, preoperative radiographic examination showed a hypervascular tumor in each of the pancreatic and hepatic lesions, but with different patterns. On the basis of histological findings in the two resected specimens, it was difficult to establish whether the hepatic tumor originated from the renal cell carcinoma or the breast cancer, but postoperative immunohistochemical studies for carcinoembryonic antigen (CEA), estrogen receptors, and gross cystic disease fluid protein (GCDFP)-15 showed that the pancreatic tumor had metastasized from the renal cell carcinoma, and the liver tumor from the breast cancer. The immunohistochemical investigation of different markers thus proved to be useful in making the final diagnosis of metastatic lesions from different and metachronous cancers.

Details

ISSN :
09441166
Volume :
8
Issue :
5
Database :
OpenAIRE
Journal :
Journal of hepato-biliary-pancreatic surgery
Accession number :
edsair.doi.dedup.....0a7e1211e735d126e77fb640b78fcead