Acute Effects of Passive Smoking on Endothelial Function

Authors :: Okan Onur Turgut
Mehmet Gungor Kaya
İbrahim Gül
Izzet Tandogan
Ahmet Yilmaz
Hekim Karapinar
Mikail Yarlioglues
Namık Kemal Eryol
Ibrahim Ozdogru
[Guel, Ibrahim] Cumhuriyet Univ, Tip Fak, Kardiyol AD, Sch Med,Cardiol Dept, TR-58140 Sivas, Turkey -- [Yarlioglues, Mikail -- Ozdogru, Ibrahim -- Kaya, Mehmet Gungor -- Eryol, Namik Kemal] Erciyes Univ, Sch Med, Dept Cardiol, Kayseri, Turkey
Turgut, Okan -- 0000-0002-6847-3029
Source :: Angiology. 62:245-247
Publication Year :: 2010
Publisher :: SAGE Publications, 2010.
Abstract: WOS: 000288462900006<br />PubMed ID: 20682610<br />Impairment of endothelial functions has been shown to occur after acute and chronic exposure to passive smoking (PS), as assessed by flow-mediated dilatation (FMD) of the brachial artery. A total of 61 participants, 30 male and 31 female, mean ages 26 (18-36) were enrolled in the study. All were clinically well and nonsmokers. All participants stayed for 30 minutes in the smoking room. Carbon monoxide (CO) level was 7.42 +/- 0.98 ppm (4.71-10.50). Mean carboxyhemoglobin (COHb) levels of participants were significantly elevated after PS. Mean FMD was 18.6% +/- 9% and decreased to 12.4% +/- 7% after PS (P < .001). In the current study, with more number of participants at lower CO concentrations (7.42 ppm) and with smaller increase in COHb (51%) significant reduction (33%, P < .001) in FMD was observed.

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