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Synthesis of cyano-2,3-dihydropyrrolo[1,2-f]phenanthridine derivatives via a domino-Knoevenagel-cyclization

Authors :
Niloufar Akbarzadeh Torbati
Faramarz Rostami-Charati
Sayyed Mostafa Habibi-Khorassani
Brian W. Skelton
Ghasem Marandi
Mohamed Makha
Nourallah Hazeri
Malek Taher Maghsoodlou
Source :
Molecular Diversity. 15:197-201
Publication Year :
2010
Publisher :
Springer Science and Business Media LLC, 2010.

Abstract

In a new multicomponent reaction phenanthridine reacts with isocyanides and malonitrile in the presence of benzaldehyde derivatives to produce 2-aryl-3-(alkyl- or arylimino)-2,3-dihydropyrrolo[1,2-f]phenanthridine-1,1(12b H)-dicarbonitrile in a simple, mild, and efficient protocol in excellent yields.

Details

ISSN :
1573501X and 13811991
Volume :
15
Database :
OpenAIRE
Journal :
Molecular Diversity
Accession number :
edsair.doi.dedup.....0a1a4272076e0dc60d7e3766661e15d1
Full Text :
https://doi.org/10.1007/s11030-010-9254-5