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An unfavorable dietary pattern is associated with symptomatic ischemic stroke and carotid atherosclerosis
- Source :
- Journal of Vascular Surgery, Journal of Vascular Surgery, Elsevier, 2010, 52 (1), pp.62-8. ⟨10.1016/j.jvs.2010.02.258⟩, Journal of Vascular Surgery, 2010, 52 (1), pp.62-8. ⟨10.1016/j.jvs.2010.02.258⟩
- Publication Year :
- 2010
- Publisher :
- HAL CCSD, 2010.
-
Abstract
- International audience; OBJECTIVE: Ischemic strokes represent more than 80% of total strokes in Western countries. The influence of dietary factors on ischemic stroke risk is debated mainly because available data are limited. Our objective was to compare the dietary pattern of symptomatic ischemic stroke patients under 65 years old with control subjects using a validated 14-item food frequency questionnaire (FFQ). We also compared symptomatic ischemic stroke patients with carotid atherosclerosis with those without according to the presence or the absence of carotid plaque defined by duplex scanning. METHODS: This was a case-control multi-center study that took place in one University hospital and two general hospitals in France. One hundred twenty-four symptomatic ischemic stroke patients (confirmation by a neurologist and imaging; 66% smokers) and 50 controls (34% smokers) without any known cardiovascular disease or previous nutritional advice were included. The main outcome measure(s) were intake scores for saturated (SFA), monounsaturated (MUFA), Omega-3 polyunsaturated (Omega-3 PUFA), and Omega-6 polyunsaturated fatty acids (Omega-6PUFA). Fruit and vegetables and an overall cardiovascular dietary score were evaluated with the FFQ. The overall cardiovascular score is calculated as (MUFA + Omega-3 PUFA + fruits and vegetables) - (SFA) scores. RESULTS: Compared with controls, ischemic stroke patients had a higher SFA score (6.6 +/- 3.0 vs 4.9 +/- 2.7; P < .001), lower scores of MUFA (0.8 +/- 0.9 vs 1.5 +/- 1.2; P < .001), Omega-3 PUFA (1.7 +/- 1.6 vs 2.2 +/- 1.5; P = .013), Omega-6PUFA (2.6 +/- 2.5 vs 3.9 +/- 2.7; P = .002), fruit and vegetables (2.9 +/- 1.7 vs 3.8 +/- 1.6; P = .005), and a lower overall dietary score (-1.2 +/- 5.0 vs 2.5 +/- 4.4; P < .001). These results remained statistically significant after adjustment for age, gender, and smoking status. Ischemic stroke patients with carotid atherosclerosis (n = 54) had a worse overall cardiovascular dietary score than those without (n = 68): -2.2 +/- 4.4 vs -0.2 +/- 5.2; P = .024. CONCLUSION: Compared with controls, ischemic stroke patients, especially those with carotid atherosclerosis, have an unfavorable dietary pattern (high SFA, low fruit and vegetables, and Omega-3 PUFA consumptions) that may have been a facilitating condition of the ischemic stroke. Dietary recommendations of a healthy diet should be useful in ischemic stroke prevention, especially in patients with cardiovascular risk factors.
- Subjects :
- Carotid Artery Diseases
Male
MESH: Food Habits
030204 cardiovascular system & hematology
Gastroenterology
Brain Ischemia
Brain ischemia
Fatty Acids, Monounsaturated
Hospitals, University
0302 clinical medicine
MESH: Fatty Acids, Omega-3
Risk Factors
MESH: Risk Factors
Vegetables
MESH: Diet Records
MESH: Fatty Acids, Omega-6
Stroke
chemistry.chemical_classification
Ultrasonography, Doppler, Duplex
MESH: Middle Aged
Cerebral infarction
Fatty Acids
food and beverages
MESH: Brain Ischemia
MESH: Life Style
Middle Aged
MESH: Case-Control Studies
Diet Records
3. Good health
MESH: Fatty Acids
MESH: Fatty Acids, Monounsaturated
Female
France
Cardiology and Cardiovascular Medicine
MESH: Fruit
Polyunsaturated fatty acid
Adult
medicine.medical_specialty
MESH: Ultrasonography, Doppler, Duplex
[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery
Hospitals, General
MESH: Stroke
Central nervous system disease
Duplex scanning
03 medical and health sciences
MESH: Diet
Internal medicine
Fatty Acids, Omega-6
Fatty Acids, Omega-3
medicine
Humans
Life Style
MESH: Hospitals, University
MESH: Humans
Vascular disease
business.industry
MESH: Carotid Artery Diseases
Case-control study
MESH: Hospitals, General
MESH: Adult
Feeding Behavior
medicine.disease
MESH: Vegetables
MESH: Male
Surgery
Diet
MESH: France
chemistry
Case-Control Studies
Fruit
business
MESH: Female
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 07415214 and 10976809
- Database :
- OpenAIRE
- Journal :
- Journal of Vascular Surgery, Journal of Vascular Surgery, Elsevier, 2010, 52 (1), pp.62-8. ⟨10.1016/j.jvs.2010.02.258⟩, Journal of Vascular Surgery, 2010, 52 (1), pp.62-8. ⟨10.1016/j.jvs.2010.02.258⟩
- Accession number :
- edsair.doi.dedup.....0a0d8e3eeae5bb115c7b3db83b472bbf