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Potential Medicinal Plants for the Treatment of Dengue Fever and Severe Acute Respiratory Syndrome-Coronavirus
- Source :
- Biomolecules, Vol 11, Iss 42, p 42 (2021), Biomolecules
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- While dengue virus (DENV) infection imposes a serious challenge to the survival of humans worldwide, severe acute respiratory syndrome-coronavirus (SARS-CoV) remains the most devastating pandemic in human history. A significant number of studies have shown that plant-derived substances could serve as potential candidates for the development of safe and efficacious remedies for combating these diseases. Different scientific databases were used to source for literature on plants used against these infections. Thirty-five studies described the traditional use of 25 species from 20 families for treating DENV infection with Carica papaya and Euphorbia hirta were the most widely used across different regions. 13 in vivo studies, 32 in vitro studies, and eight clinical studies were conducted on 30 species from 25 families against different DENV serotypes, while plants from 13 families were reported to inhibit different forms of SARS-CoV, all of which were investigated through in vitro studies. Phytoconstituents belonging to various chemical classes were identified to show a wide range of antiviral activity against these infections. Extensive studies on the potentials of medicinal plants are needed to confirm their efficacy. This paper reveals the capabilities of medicinal plants and their phytochemicals in inhibiting DENV and SARS-CoV infections.
- Subjects :
- viruses
Phytochemicals
lcsh:QR1-502
Review
phytochemical
Dengue virus
Severe Acute Respiratory Syndrome
medicine.disease_cause
01 natural sciences
Biochemistry
lcsh:Microbiology
Dengue fever
Dengue
03 medical and health sciences
ethnobotany
Euphorbia
Pandemic
medicine
Humans
Medicinal plants
Molecular Biology
030304 developmental biology
0303 health sciences
Plants, Medicinal
biology
dengue virus
Carica
virus diseases
SARS-CoV
biology.organism_classification
medicine.disease
Virology
0104 chemical sciences
010404 medicinal & biomolecular chemistry
Severe acute respiratory syndrome-related coronavirus
Phytochemical
Ethnobotany
pharmacology
medicinal plants
Subjects
Details
- Language :
- English
- Volume :
- 11
- Issue :
- 42
- Database :
- OpenAIRE
- Journal :
- Biomolecules
- Accession number :
- edsair.doi.dedup.....09a574e46de4fe2f3c77210271726b49