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The Influence of Late Acute Rejection Episodes on Long-Term Graft Outcome After Liver Transplantation
- Source :
- Transplantation Proceedings. 37:1716-1717
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- Acute cellular rejection represents the most important single risk factor for the occurrence of chronic rejection after organ transplantation. We correlated late acute rejections with the occurrence of chronic graft failure after liver transplantation. We followed 1426 liver transplants for late acute rejection episodes defined as occurring >3 months after OLT. The overall incidence of chronic rejection in our patient population was 3.7%. In summary, we observed a predictive increase of transaminase levels prior to routine biopsies among patients with histologic evidence of late acute rejections. In contrast to other organ systems, late acute rejection episodes were not associated with the occurrence of chronic graft deterioration in liver grafts.
- Subjects :
- Graft Rejection
medicine.medical_specialty
Time Factors
Graft failure
medicine.medical_treatment
Liver transplantation
Organ transplantation
Transaminase
Liver Function Tests
Humans
Medicine
Risk factor
Organ system
Retrospective Studies
Transplantation
business.industry
Incidence (epidemiology)
Survival Analysis
Liver Transplantation
Surgery
Treatment Outcome
surgical procedures, operative
Acute Disease
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00411345
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Transplantation Proceedings
- Accession number :
- edsair.doi.dedup.....098eb837b19c8eda7f5754c293ff6f98