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Additional file 1 of Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases

Authors :
Li, Chun Yu
Yang, Tian Mi
Ou, Ru Wei
Wei, Qian Qian
Shang, Hui Fang
Publication Year :
2021
Publisher :
figshare, 2021.

Abstract

Additional file 1: Table S1. Summary data from all GWAS used in current study. Table S2. Genetic correlation between AD, ALS, PD and autoimmune disorders. Table S3. Risk loci associated with ALS conditional on autoimmune diseases. Table S4. eQTL revealing functional effects of shared risk SNPs in tissues from GTEx. Table S5. Functional annotation of shared risk genes. Figure S1. Manhattan-style plots showing the estimates of local genetic correlation between ALS and autoimmune disorders. Figure S2. Conditional Manhattan plots showing risk loci for ALS conditional on each autoimmune disease. Figure S3. Regional association plots for shared risk loci between ALS and each autoimmune disease

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....098c7333820f374654cce6e3bc908ccc
Full Text :
https://doi.org/10.6084/m9.figshare.13719456.v1