Additional file 16 of CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease

Additional file 16. CK2a’ haploinsufficiency decreased the levels of pS129-α-syn. a, Representative pS129-α-syn IF images (D1R1R antibody) in the dorsal striatum of 12 months old WT, zQ175 and zQ175:CK2α’(+/-), Scale bar, 20 μm. b, pS129-α-syn and CK2α’ immunoblotting of striatum samples from 12-month-old zQ175 and zQ175:CK2α’(+/-) mice (n = 3 mice/group). c, Levels of pS129-α-syn and CK2α’ were calculated using Image J from immunoblotting images in a and showed a parallel decrease of pS129-α-syn and CK2α’ levels in zQ175:CK2α’(+/-) compared to zQ175 mice. Error bars represent mean ± SEM. Statistical analyses were conducted by Student’s t-test. p-values