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Response of the pigeon crop sac to mammotrophic hormones: Comparison between relaxin and prolactin
- Source :
- General and Comparative Endocrinology. 80:16-23
- Publication Year :
- 1990
- Publisher :
- Elsevier BV, 1990.
-
Abstract
- The effects of relaxin (RLX), a hormone that has previously been demonstrated to have mammotrophic properties, were studied in the pigeon crop sac, a well-known target organ for mammotrophic and lactogenic hormones, and compared with the effects produced by prolactin (PRL). The two hormones were injected directly over the crop at different doses and the response was evaluated after differing times of exposure. RLX causes a dose-related increase in wet and dry weights and [3H]thymidine and [3H]uridine uptake by the crop mucosa, as well as morphological changes indicating growth and differentiation of the epithelial cells similar to those occurring during physiological activation in incubation and hatching. At the doses assayed, the effects of RLX were nearly identical to those obtained following PRL in the short-term experiments, but differences in functional responses were found in the long-term experiment.
- Subjects :
- medicine.medical_specialty
Time Factors
Peptide hormone
Biology
Tritium
chemistry.chemical_compound
Endocrinology
Internal medicine
medicine
Animals
Columbidae
Uridine
Incubation
Relaxin
Mucous Membrane
Dose-Response Relationship, Drug
Hatching
Prolactin
chemistry
Crop, Avian
Animal Science and Zoology
Thymidine
Hormone
Subjects
Details
- ISSN :
- 00166480
- Volume :
- 80
- Database :
- OpenAIRE
- Journal :
- General and Comparative Endocrinology
- Accession number :
- edsair.doi.dedup.....0981e0a3e0f35bbb4decfef09cadf665