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The Ethics of Placebo in Studies with Fracture End Points in Osteoporosis

Authors :
Wayne A. Ray
C. Michael Stein
Source :
New England Journal of Medicine. 363:1367-1370
Publication Year :
2010
Publisher :
Massachusetts Medical Society, 2010.

Abstract

The authors suggest that placebo-controlled trials in osteoporosis are nearly always unethical, since several drugs that materially decrease the risk of fractures in such patients are currently available.

Details

ISSN :
15334406 and 00284793
Volume :
363
Database :
OpenAIRE
Journal :
New England Journal of Medicine
Accession number :
edsair.doi.dedup.....0955eb05380c952196e68b52f5248902
Full Text :
https://doi.org/10.1056/nejmsb1006120