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Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto Rico
- Publication Year :
- 2013
-
Abstract
- Although a higher prevalence of osteoarthritis (OA) has been reported among diabetes mellitus (DM) patients, inconsistencies and limitations of observational studies have precluded a conclusive association.The objective of this study was to evaluate the association of hand or knee OA with DM in a population of Hispanics from Puerto Rico.A cross-sectional study was performed in 202 subjects (100 adult DM patients as per the National Diabetes Data Group Classification and 102 nondiabetic subjects). Osteoarthritis of hand and knee was ascertained using the American College of Rheumatology classification criteria. Sociodemographic characteristics, health-related behaviors, comorbidities, pharmacotherapy, and DM clinical manifestations were determined. Multivariable logistic regression was used to evaluate the association of DM with hand or knee OA and to evaluate factors associated with hand or knee OA among DM patients.The mean (SD) age for DM patients was 51.6 (13.1) years; 64.0% were females. The mean (SD) DM duration was 11.0 (10.4) years. The prevalence of OA in patients with DM and nondiabetic subjects was 49.0% and 26.5%, respectively (P0.01). In the multivariable analysis, patients with DM had 2.18 the odds of having OA when compared with nondiabetic subjects (95% confidence interval [CI], 1.12-4.24). In a subanalysis among DM patients, female patients were more likely to have hand or knee OA (odds ratio [95% CI], 5.06 [1.66-15.66]), whereas patients who did not use insulin alone for DM therapy were more likely to have OA (odds ratio [95% CI], 4.44 [1.22-16.12]).In this population of Hispanics from Puerto Rico, DM patients were more likely to have OA of hands or knees than were nondiabetic subjects. This association was retained in multivariable models accounting for established risk factors for OA. Among DM patients, females were at greater risk for OA, whereas the use of insulin was negatively associated.
- Subjects :
- Adult
Male
medicine.medical_specialty
Cross-sectional study
Population
Osteoarthritis
Comorbidity
Article
Sex Factors
Rheumatology
Risk Factors
Internal medicine
Diabetes mellitus
Diabetes Mellitus
Odds Ratio
Prevalence
Medicine
Humans
education
education.field_of_study
business.industry
Puerto Rico
Case-control study
Odds ratio
Hispanic or Latino
Middle Aged
Osteoarthritis, Knee
medicine.disease
Hand
Cross-Sectional Studies
Logistic Models
Case-Control Studies
Multivariate Analysis
Physical therapy
Observational study
Female
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....0950a33a103bde0cd0b2a0050b54292b