Back to Search
Start Over
Pulmonary resections of single metastases from colorectal cancer
- Publication Year :
- 2007
-
Abstract
- Surgical resection is the treatment of choice of pulmonary metastases from colorectal cancer. We retrospectively reviewed our experience of pulmonary resections of single metastases from colorectal cancer, in order to document postoperative clinical outcome and survival.In the years 1997-2007, in 23 patients we performed 26 curative resections of pulmonary metastases from colorectal cancer (19 rectal and 7 colon; 12 males and 11 females; mean age 64.5 years). All patients had single lung metastasis. Three of the 23 patients underwent re-resection of the lung for treatment of a subsequent lung metastasis. Interval between resection of primary tumor and diagnosis of lung metastasis (disease-free interval (DFI)) was36 months in 19 patients (73%) and was36 months in 7 patients (27%). In 21 patients the metastases were metachronous; in 2 patients metastases were synchronous with primary colorectal cancer. The type of lung resection was wedge resection in 18 cases (70%); lobectomy in 6 cases (23%); pneumonectomy in 2 cases (7%). Of the 18 wedge resections, 12 (66%) were done thoracoscopically. After lung metastasectomy patients were followed up for 5-121 months (median: 61 months).We had 1 early postoperative mortality (after re-resection) from cardiac complication (3.8%). Postoperative morbidity (within 30 days) was observed in 7 cases (27%): 1 pneumonia, 1 empyema, 1 arrhythmia and 4 prolonged air leaks requiring chest drainage7 days. Median survival was 74 months (Kaplan-Meier).Resection of single metachronous lung metastases from colorectal cancer has low mortality and morbidity and in our experience it correlated with prolonged postoperative survival. Re-resection of the lung for treatment of subsequent metachronous metastases carries higher risk.
- Subjects :
- Adult
Male
medicine.medical_specialty
Lung Neoplasms
Colorectal cancer
Metastasis
Postoperative Complications
Single lung
Carcinoembryonic antigen
medicine
Humans
Pneumonectomy
Aged
Retrospective Studies
Lung
biology
Thoracic Surgery, Video-Assisted
business.industry
Length of Stay
Middle Aged
medicine.disease
Primary tumor
Empyema
Surgery
Pneumonia
medicine.anatomical_structure
Oncology
biology.protein
Female
Colorectal Neoplasms
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....0932267bf02b90a925ffcadd5a004462