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Nocardiosis in Allogeneic Hematopoietic Stem Cell Transplant Recipients: A Matched Case-Control Study of Risk Factors, Clinical Features and Outcomes

Authors :
Miguel Chagnon
Guy Sauvageau
Denis-Claude Roy
Silvy Lachance
Thomas Kiss
Nadia M. Bambace
Louise Poirier
Jean Roy
Sandra Cohen
Source :
Biology of Blood and Marrow Transplantation. 19:S280
Publication Year :
2013
Publisher :
Elsevier BV, 2013.

Abstract

2 (2%) patients developed other fungal related problems. One patient developed oral candidiasis treated with micafungin. One patient had splenic leisons (presumed fungal) treated with treatment dose posaconazole and improved. None of these patients had aGVHD at time of IFI diagnosis. None of these patients died of fungal related causes. 4 out of 5 patients were alive at last follow up. One died of relapse. Conclusion: Micafungin followed by posaconazole is effective as primary IFI prophylaxis in unrelated donor HCT.

Details

ISSN :
10838791
Volume :
19
Database :
OpenAIRE
Journal :
Biology of Blood and Marrow Transplantation
Accession number :
edsair.doi.dedup.....091acaba682caec682b02975a643a4a8
Full Text :
https://doi.org/10.1016/j.bbmt.2012.11.396