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Fine-Tuning and Enhancement of pH-Dependent Membrane Permeation of Cyclic Peptides by Utilizing Noncanonical Amino Acids with Extended Side Chains

Authors :
Motomi Matsuda
Keisuke Ikeda
Tomoshi Kameda
Hiroyuki Nakao
Minoru Nakano
Source :
Journal of Medicinal Chemistry. 66:7054-7062
Publication Year :
2023
Publisher :
American Chemical Society (ACS), 2023.

Subjects

Subjects :
Drug Discovery
Molecular Medicine

Details

ISSN :
15204804 and 00222623
Volume :
66
Database :
OpenAIRE
Journal :
Journal of Medicinal Chemistry
Accession number :
edsair.doi.dedup.....08ed6148504cd94cd07d2f4291c86e39
Full Text :
https://doi.org/10.1021/acs.jmedchem.3c00628
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