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D-MaPs - DNA-microarray projects: web-based software for multi-platform microarray analysis

Authors :
Ana Carolina Deckmann
Taís S. Herig
Gonçalo Amarante Guimarães Pereira
Marcelo Falsarella Carazzolle
Source :
Genetics and Molecular Biology, Genetics and Molecular Biology, Vol 32, Iss 3, Pp 634-639 (2009), Genetics and Molecular Biology v.32 n.3 2009, Sociedade Brasileira de Genética (SBG), instacron:SBG, Genetics and Molecular Biology, Volume: 32, Issue: 3, Pages: 634-639, Published: 2009
Publication Year :
2009
Publisher :
FapUNIFESP (SciELO), 2009.

Abstract

The web application D-Maps provides a user-friendly interface to researchers performing studies based on microarrays. The program was developed to manage and process one- or two-color microarray data obtained from several platforms (currently, GeneTAC, ScanArray, CodeLink, NimbleGen and Affymetrix). Despite the availability of many algorithms and many software programs designed to perform microarray analysis on the internet, these usually require sophisticated knowledge of mathematics, statistics and computation. D-maps was developed to overcome the requirement of high performance computers or programming experience. D-Maps performs raw data processing, normalization and statistical analysis, allowing access to the analyzed data in text or graphical format. An original feature presented by D-Maps is GEO (Gene Expression Omnibus) submission format service. The D-MaPs application was already used for analysis of oligonucleotide microarrays and PCR-spotted arrays (one- and two-color, laser and light scanner). In conclusion, D-Maps is a valuable tool for microarray research community, especially in the case of groups without a bioinformatic core.

Details

ISSN :
14154757
Volume :
32
Database :
OpenAIRE
Journal :
Genetics and Molecular Biology
Accession number :
edsair.doi.dedup.....08e2a4edf8272bde3024db571297d9fa
Full Text :
https://doi.org/10.1590/s1415-47572009000300030