Back to Search
Start Over
Spindle Cell Carcinoma of the Larynx with Rhabdomyoblastic Heterologous Element: A Rare Form of Divergent Differentiation
- Source :
- Head and Neck Pathology. 7:263-267
- Publication Year :
- 2012
- Publisher :
- Springer Science and Business Media LLC, 2012.
-
Abstract
- Spindle cell (sarcomatoid) carcinoma of the larynx is a rare subtype of squamous cell carcinoma that shows a prominent spindle cell component with a mesenchymal phenotype. Heterologous elements may be seen in these spindled areas and usually consist of osteosarcomatous or chondrosarcomatous differentiation. We describe an unusual spindle cell carcinoma of the vocal cord in a 68-year-old male which demonstrated rhabdomyosarcomatous differentiation as confirmed by desmin and myogenin immunoreactivity. Thus rhabdomyosarcomatous differentiation adds to the phenotypic spectrum of spindle cell carcinomas of the larynx and should be considered before invoking a diagnosis of true rhabdomyosarcoma of the larynx.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Cellular differentiation
Cell
Case Report
Biology
Pathology and Forensic Medicine
Rhabdomyosarcoma
Carcinosarcoma
Biomarkers, Tumor
otorhinolaryngologic diseases
medicine
Carcinoma
Humans
Laryngeal Neoplasms
Aged
Cell Differentiation
Laryngeal Neoplasm
medicine.disease
Immunohistochemistry
medicine.anatomical_structure
Oncology
Otorhinolaryngology
Carcinoma, Squamous Cell
Desmin
Spindle cell carcinoma
Subjects
Details
- ISSN :
- 19360568 and 1936055X
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Head and Neck Pathology
- Accession number :
- edsair.doi.dedup.....08c62f10d51a327f63f9c74a29eb16c8