Interaction between X-ray- and restriction endonuclease-induced lesions in the formation of chromosomal aberrations

Experiments were performed to analyze the possible interaction between lesions induced by X-rays and restriction endonucleases in the production of chromosome-type exchanges. A stronger interaction was found between X-rays and the AluI-induced ‘blunt termini’ lesions than between X-rays and the BamHI- induced ‘cohesive termini’ lesions