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Extended laparoscopic distal pancreatectomy for adenocarcinoma in the body and tail of the pancreas: a single-center experience
- Source :
- Langenbeck's archives of surgery. 403(8)
- Publication Year :
- 2018
-
Abstract
- Extended resection is required for pancreatic adenocarcinoma infiltrating adjacent organs and structures. The role of laparoscopy in this setting is unclear. In this study, the outcomes of extended laparoscopic distal pancreatectomy (ELDP) for pancreatic body/tail adenocarcinoma were examined. Perioperative and oncologic data were analyzed in patients undergoing laparoscopic distal pancreatectomy (LDP) for adenocarcinoma at Oslo University Hospital. ELDP was defined as suggested by the International Study Group for Pancreatic Surgery. The outcomes of ELDP were compared to those following standard LDP (SLDP). From August 2001 to June 2016, 460 consecutive patients underwent LDP for pancreatic neoplasms including 116 (25%) adenocarcinoma. SLDP and ELDP were applied in 78 and 31 patients, respectively. The adrenal gland (33%) and colon (21%) were the most frequently resected organs during ELDP. The latter was associated with larger tumor size (5.5 vs 4 cm, p = 0.03), longer operative time (236 vs 158 min, p = 0.001) and higher conversion rate (16 vs 3%, p = 0.019) compared with SLDP. Morbidity and 90-day mortality were similar. Median follow-up was 18 months. In patients with ductal adenocarcinoma, ELDP (n = 22) was associated with significantly shorter recurrence-free and overall survival than SLDP (n = 59) (6.2 vs 9.6 months, p = 0.047 and 12.9 vs 27 months, p
- Subjects :
- Male
medicine.medical_specialty
Palliative care
medicine.medical_treatment
Operative Time
030230 surgery
Adenocarcinoma
Single Center
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Pancreatectomy
medicine
Humans
Laparoscopy
Aged
medicine.diagnostic_test
business.industry
Perioperative
Length of Stay
Middle Aged
medicine.disease
Surgery
Pancreatic Neoplasms
Survival Rate
Treatment Outcome
Cardiothoracic surgery
030220 oncology & carcinogenesis
Female
business
Abdominal surgery
Subjects
Details
- ISSN :
- 14352451
- Volume :
- 403
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Langenbeck's archives of surgery
- Accession number :
- edsair.doi.dedup.....083761c1ea6b69c58a55fc577eac76ab