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Toward the identification, characterization and experimental culture ofLacazia loboifrom Atlantic bottlenose dolphin (Tursiops truncatus)
- Source :
- Medical Mycology. 54:659-665
- Publication Year :
- 2016
- Publisher :
- Oxford University Press (OUP), 2016.
-
Abstract
- Lobomycosis (lacaziosis) is a chronic, granulomatous, fungal infection of the skin and subcutaneous tissues of humans and dolphins. To date, the causative agent, the yeast-like organism Lacazia loboi, has not been grown in the laboratory, and there have been no recent reports describing attempts to culture the organism. As a result, studies on the efficacy of therapeutics and potential environmental reservoirs have not been conducted. Therefore, the objective of the current study was to utilize both classical and novel microbiological methods in order to stimulate growth of Lacazia cells collected from dolphin lesions. This included the experimental inoculation of novel media, cell culture, and the use of artificial skin matrices. Although unsuccessful, the methods and results of this study provide important insight into new approaches that could be utilized in future investigations of this elusive organism.
- Subjects :
- Microbiological Techniques
0301 basic medicine
Bottle-nosed dolphin
Lacazia
030106 microbiology
030231 tropical medicine
Biology
Microbiology
03 medical and health sciences
0302 clinical medicine
medicine
Animals
Atlantic Ocean
Lobomycosis
Organism
Microscopy
Granuloma
Histocytochemistry
General Medicine
medicine.disease
Bottlenose dolphin
biology.organism_classification
Bottle-Nosed Dolphin
Infectious Diseases
Identification (biology)
Subjects
Details
- ISSN :
- 14602709 and 13693786
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Medical Mycology
- Accession number :
- edsair.doi.dedup.....07e68eb182d74d844b699c72c38fc146