Additional file 1 of Psychiatric manifestations of rare variation in medically actionable genes: a PheWAS approach

Additional file 1: Figure S1. Ancestry assignment of study individuals using principal component analyses (PCA). Figure S2. Phenotypic correlation heatmap among the 37 curated PheCodes of common psychiatric phenotypes. Figure S3. No inflation in λGC from single variant association analysis for two selected complex traits. Figure S4. Phenome-wide burden of rare variation in LDLR recapitulated known association with hypercholesterolemia. Figure S5. PheWAS of rare variation in the ACMG-56 genes with psychiatric disorders