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Effects of Small Molecule Ligands on ACKR3 Receptors
- Source :
- Molecular Pharmacology. 102:128-138
- Publication Year :
- 2022
- Publisher :
- American Society for Pharmacology & Experimental Therapeutics (ASPET), 2022.
-
Abstract
- Chemokines such as stromal derived factor 1 and their G protein coupled receptors are well-known regulators of the development and functions of numerous tissues. C-X-C motif chemokine ligand 12 (CXCL12) has two receptors: C-X-C chemokine motif receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3). ACKR3 has been described as an atypical "biased" receptor because it does not appear to signal through G proteins and, instead, signals solely through the
Details
- ISSN :
- 15210111 and 0026895X
- Volume :
- 102
- Database :
- OpenAIRE
- Journal :
- Molecular Pharmacology
- Accession number :
- edsair.doi.dedup.....07e0163f6f1baa4d779d5d2dd877589c