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Sphenoid Bone Structure and Its Influence on the Cranium in Syndromic Versus Nonsyndromic Craniosynostosis
- Source :
- Journal of Craniofacial Surgery. 32:67-72
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- BACKGROUND Little is known about the detailed growth of the sphenoidal and temporal bones, even though they contribute significantly to the cranial base and cranial fossa skeletons. They also serve to connect the cranial vault with facial structure. This study details their morphologic development in isolated bicoronal synostosis and associated syndromes. METHODS Eighty-one CT scans were included (nonsyndromic bicoronal synostosis, n = 28; Apert syndrome associated with bicoronal synostosis, n = 19; Crouzon syndrome associated with bicoronal synostosis, n = 8; and controls, n = 26), and measured using Materialize software. RESULTS Sphenoidal and temporal bone volumes in nonsyndromic bicoronal synostosis are reduced 23% (P = 0.005) and 24%(P = 0.003) at 6 months of age, compared to controls. Apert and Crouzon syndrome patients developed similar reduced volumes. The greater wing of the sphenoid and pterygoid processes in nonsyndromic bicoronal synostosis are initially inferiorly rotated at 2 months of age, by 9.60° (P = 0.002) and 4.33° (P = 0.023), respectively. In Apert syndrome, these rotations were reduced by 4.82° (P = 0.003) and 12.60° (P
- Subjects :
- Sphenoid bone
Bicoronal synostosis
Apert syndrome
Craniosynostosis
Craniosynostoses
03 medical and health sciences
0302 clinical medicine
Sphenoid Bone
Cranial vault
Temporal bone
Humans
Medicine
Cranial fossa
030223 otorhinolaryngology
Orthodontics
business.industry
Craniofacial Dysostosis
Crouzon syndrome
Syndrome
030206 dentistry
General Medicine
Acrocephalosyndactylia
medicine.disease
Otorhinolaryngology
Surgery
business
Subjects
Details
- ISSN :
- 15363732 and 10492275
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Journal of Craniofacial Surgery
- Accession number :
- edsair.doi.dedup.....07d8904749d4adf1e958d66b3b325389