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Early Experiences With COVID-19 Testing in Transplantation
- Source :
- Transplantation Direct, Transplantation Direct, Vol 6, Iss 7, p e572 (2020)
- Publication Year :
- 2020
-
Abstract
- Background The early effects of coronavirus disease 2019 (COVID-19) on transplantation are dramatic: >75% of kidney and liver programs are either suspended or operating under major restrictions. To resume transplantation, it is important to understand the prevalence of COVID-19 among transplant recipients, donors, and healthcare workers (HCWs) and its associated mortality. Methods To investigate this, we studied severe acute respiratory syndrome coronavirus 2 diagnostic test results among patients with end-stage renal disease or kidney transplants from the Johns Hopkins Health System (n = 235), and screening test results from deceased donors from the Southwest Transplant Alliance Organ Procurement Organization (n = 27), and donors, candidates, and HCWs from the National Kidney Registry and Viracor-Eurofins (n = 253) between February 23 and April 15, 2020. Results We found low rates of COVID-19 among donors and HCWs (0%-1%) who were screened, higher rates of diagnostic tests among patients with end-stage renal disease or kidney transplant (17%-20%), and considerable mortality (7%-13%) among those who tested positive. Conclusions These findings suggest the threat of COVID-19 for the transplant population is significant and ongoing data collection and reporting is critical to inform transplant practices during and after the pandemic.
Details
- ISSN :
- 23738731
- Volume :
- 6
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Transplantation direct
- Accession number :
- edsair.doi.dedup.....07a2523e979f53786796a2fa89da4a84