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MicroRNAs in Sarcopenia: A Systematic Review

Authors :
Katsunori Yanai
Shohei Kaneko
Hiroki Ishii
Akinori Aomatsu
Kiyonori Ito
Keiji Hirai
Susumu Ookawara
Kenichi Ishibashi
Yoshiyuki Morishita
Source :
Frontiers in Medicine, Vol 7 (2020), Frontiers in Medicine
Publication Year :
2020
Publisher :
Frontiers Media SA, 2020.

Abstract

Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.

Details

ISSN :
2296858X
Volume :
7
Database :
OpenAIRE
Journal :
Frontiers in Medicine
Accession number :
edsair.doi.dedup.....077e19e3bd6ee6a853c1acc2d367da5b