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MicroRNAs in Sarcopenia: A Systematic Review
- Source :
- Frontiers in Medicine, Vol 7 (2020), Frontiers in Medicine
- Publication Year :
- 2020
- Publisher :
- Frontiers Media SA, 2020.
-
Abstract
- Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.
- Subjects :
- 0301 basic medicine
Biology
Bioinformatics
sarcopenia
03 medical and health sciences
0302 clinical medicine
systematic review
microRNA
medicine
Myocyte
myocyte
lcsh:R5-920
Skeletal muscle
Translation (biology)
General Medicine
musculoskeletal system
medicine.disease
body regions
030104 developmental biology
medicine.anatomical_structure
Sarcopenia
Medicine
myotube
myoblast
lcsh:Medicine (General)
human activities
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 2296858X
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Frontiers in Medicine
- Accession number :
- edsair.doi.dedup.....077e19e3bd6ee6a853c1acc2d367da5b