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Acute Hypersensitivity Pneumonitis Associated With a High Ki-67 Proliferative Index

Authors :
Dereen Mohammed Saeed
Michael R. Pins
Amanda Kamar
Edward Nabrinsky
Arvey Stone
Source :
Cureus
Publication Year :
2020
Publisher :
Cureus, Inc., 2020.

Abstract

Hypersensitivity pneumonitis (HSP) is an interstitial lung disease caused by exposure to a large range of environmental antigens. Inhaling aerosolized particles leads to a heightened immune response. HSP comes in acute, subacute, or chronic forms, all with their own potential clinical and radiographic findings. Mycobacterium avium complex (MAC) is the most common nontuberculous mycobacteria and is known to cause HSP with certain exposures. However, although certain histologic findings can be seen with HSP, a high ki-67 proliferation index is unusual and more commonly associated with malignancy. In this report, we discuss a case of MAC that had acute HSP associated with a high ki-67 proliferative index.

Details

ISSN :
21688184
Database :
OpenAIRE
Journal :
Cureus
Accession number :
edsair.doi.dedup.....0751957990d1f45e5e5b87e25ffbf33e