Synthesis of graphene quantum dots and their applications in drug delivery

Authors :: Fan Wang
Ming Zhang
Ya Liu
Changhong Zhao
Lu Li
Xuebin Song
Nan Wang
Yifeng Fu
Mohsen Mohammadniaei
Lilei Ye
Johan Liu
Qiqing Zhang
Source :: Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-32 (2020), Journal of Nanobiotechnology, Zhao, C, Song, X, Liu, Y, Fu, Y, Ye, L, Wang, N, Wang, F, Li, L, Mohammadniaei, M, Zhang, M, Zhang, Q & Liu, J 2020, ' Synthesis of graphene quantum dots and their applications in drug delivery ', Journal of Nanobiotechnology, vol. 18, no. 1, 142 . https://doi.org/10.1186/s12951-020-00698-z
Publication Year :: 2020
Publisher :: BMC, 2020.
Abstract: This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.