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High Prevalence of Drug-Drug Interactions in Primary Health Care is Caused by Prescriptions from other Healthcare Units
- Source :
- Basic & Clinical Pharmacology & Toxicology. 122:512-516
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Drug-drug interactions are increasingly common, as patients are getting older and the number of drugs per patient is increasing. In this study, we investigated to which extent potential drug-drug interactions originated from single or multiple prescribers. All patients attending any of 20 primary healthcare centres were included in a retrospective observational cohort study. Data on all prescriptions to these patients, irrespectively of the prescriber, were collected for two 4-month periods. Potential drug interactions were identified using the drug-drug interaction database SFINX. Interactions were classified with respect to the workplace of the prescriber, and the prevalence of interactions according to origin was analysed. We found that the drug interactions were significantly more common when the drugs were prescribed from different healthcare centres, compared with drugs prescribed from the patients' primary healthcare centre only. One explanation for this increased risk of drug interactions could be that the prescribers at different primary healthcare centres do not share the same information concerning the total medication list of the patient.
- Subjects :
- Adult
Male
Pediatrics
medicine.medical_specialty
Prescription Drugs
Time Factors
Drug-Related Side Effects and Adverse Reactions
Toxicology
Drug Prescriptions
Clinical decision support system
03 medical and health sciences
Drug Utilization Review
0302 clinical medicine
Risk Factors
Health care
Prevalence
medicine
Humans
Drug Interactions
030212 general & internal medicine
Medical prescription
Aged
Retrospective Studies
Sweden
Pharmacology
Polypharmacy
Primary Health Care
business.industry
Retrospective cohort study
General Medicine
Middle Aged
030220 oncology & carcinogenesis
Family medicine
Female
business
Medication list
Cohort study
Subjects
Details
- ISSN :
- 17427835
- Volume :
- 122
- Database :
- OpenAIRE
- Journal :
- Basic & Clinical Pharmacology & Toxicology
- Accession number :
- edsair.doi.dedup.....0745433c237d4f799fca9067c952f2a9