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Allergic Contact Dermatitis
- Source :
- Immunology and allergy clinics of North America. 37(1)
- Publication Year :
- 2016
-
Abstract
- Allergic contact dermatitis (ACD) is a common skin disease caused by a T cell-mediated immune reaction to usually innocuous allergens. ACD can have grave medical and socioeconomic consequences. ACD and irritant contact dermatitis often occur together. A detailed history and clinical examination are crucial and guide patch testing, which is the gold standard to diagnose ACD. T-cell clones persisting in the skin may explain the tendency of ACD to relapse even after years of allergen avoidance. Traditional treatments for ACD are topical steroids, calcineurin inhibitors, phototherapy, retinoids (including the recent alitretinoin), and immunosuppressants. Targeted therapies are lacking.
- Subjects :
- 0301 basic medicine
2403 Immunology
Immunology
10177 Dermatology Clinic
610 Medicine & health
Allergens
Patch Tests
Diagnosis, Differential
030207 dermatology & venereal diseases
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Occupational Exposure
Dermatitis, Allergic Contact
2723 Immunology and Allergy
Immunology and Allergy
Dermatitis, Irritant
Humans
Skin
Subjects
Details
- ISSN :
- 15578607
- Volume :
- 37
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Immunology and allergy clinics of North America
- Accession number :
- edsair.doi.dedup.....0737bb042c87d9cb0f43b817268373a6