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Fever-related arrhythmic events in the multicenter Survey on Arrhythmic Events in Brugada Syndrome
- Source :
- Heart Rhythm, r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu, instname, r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu, Heart rhythm, 15(9), 1394-1401. Elsevier
- Publication Year :
- 2018
-
Abstract
- BACKGROUND: The literature on fever-related arrhythmic events (AEs) in Brugada syndrome (BrS) is currently limited to few case reports and small series. OBJECTIVE: The present study aimed to describe the characteristics of fever-related AE in a large cohort of patients with BrS. METHODS: The Survey on Arrhythmic Events in Brugada Syndrome is a multicenter study on 678 patients with BrS with first AE documented at the time of aborted cardiac arrest (n = 426) or after prophylactic implantable cardioverter-defibrillator implantation (n = 252). RESULTS: In 35 of 588 patients (6%) with available information, the AE occurred during a febrile illness. Most of the 35 patients were male (80%), Caucasian (83%), and proband (70%). The mean age at the time of AE was 29 ± 24 years (range 0.3-76 years). Most patients (80%) presented with aborted cardiac arrest and 6 (17%) with arrhythmic storm. Family history of sudden death, history of syncope, and spontaneous type 1 Brugada electrocardiogram were noted in 17%, 40%, and 71% of patients, respectively. Ventricular fibrillation was induced at electrophysiology study in 9 of 19 patients (47%). An SCN5A mutation was found in 14 of 28 patients (50%). The highest proportion of fever-related AE was observed in the pediatric population (age
- Subjects :
- Proband
Male
030204 cardiovascular system & hematology
Fever
Electrocardiography
0302 clinical medicine
Elderly
Surveys and Questionnaires
Ethnicity
030212 general & internal medicine
Family history
Child
Children
Brugada syndrome
medicine.diagnostic_test
Middle Aged
Prognosis
Child, Preschool
Ventricular Fibrillation
Cardiology
Female
Sex
Cardiology and Cardiovascular Medicine
Adult
medicine.medical_specialty
Adolescent
Physiology (medical)
Sudden death
03 medical and health sciences
Electrophysiology study
Young Adult
Internal medicine
medicine
Humans
Aged
business.industry
Infant, Newborn
Infant
medicine.disease
Ventricular fibrillation
Multicenter survey
business
Pediatric population
Subjects
Details
- Language :
- English
- ISSN :
- 15475271 and 15563871
- Volume :
- 15
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Heart rhythm
- Accession number :
- edsair.doi.dedup.....0712cd12e868a25961c4426771f8bea4