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Myoepithelioma-like tumour of the vulval region: A case report
- Source :
- The Australasian journal of dermatologyREFERENCES. 63(1)
- Publication Year :
- 2021
-
Abstract
- Myoepithelioma-like tumours of the vulvar region (MELTVR) are a newly described group of spindle cell neoplasm. Morphologically, they consist of epithelioid to spindled cells in a myxoid to collagenous stroma and can resemble epithelioid sarcomas, myoepithelial carcinomas or extraskeletal myxoid chondrosarcomas. However, they have a distinct pattern of immunohistochemical staining characterised by positivity for EMA, ER, PR and negativity for cytokeratin, GFAP and S100. Nuclear staining for INI-1 is lost. In addition, they lack the characteristic gene arrangements of these other lesions. MELTVR can recur locally when incompletely excised, however, do not appear to metastasize. We report a case of a MELTVR in a 49-year-old woman arising in the right mons pubis.
- Subjects :
- Vulvar Neoplasms
Humans
Female
Dermatology
Middle Aged
Myoepithelioma
Subjects
Details
- ISSN :
- 14400960
- Volume :
- 63
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The Australasian journal of dermatologyREFERENCES
- Accession number :
- edsair.doi.dedup.....06fe9618d55daecb363b53c218f92b6e