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Prospective multicenter evaluation of cataract surgery in patients taking tamsulosin (Flomax)
- Source :
- Ophthalmology. 114(5)
- Publication Year :
- 2006
-
Abstract
- Purpose Intraoperative floppy iris syndrome (IFIS) caused by systemic α-blockers has been associated with an increased risk of cataract surgical complications when the surgeon was unaware of the medication history and did not anticipate its occurrence. This study was undertaken to evaluate the surgical outcomes and rate of complications when the ophthalmologist knew the patient was taking tamsulosin (Flomax, Boehringer-Ingelheim Pharmaceuticals, Ridgefield, CT) and used 1 of several strategies to manage IFIS. Design Prospective multicenter nonrandomized observational series. Participants A total of 167 consecutive eyes in 135 patients taking tamsulosin and undergoing cataract surgery. Methods Phacoemulsification was performed in conjunction with at least 1 of 4 different IFIS management strategies, namely, topical atropine preoperatively, iris retractors, pupil expansion ring, or use of viscoadaptive ophthalmic viscosurgical device with reduced fluidic parameters. Main Outcome Measures Severity of IFIS, incidence of operative or postoperative complications, and final visual acuity. Results The IFIS severity was rated as mild in 17%, moderate in 30%, and severe in 43% of the study eyes. No IFIS was noted in 10% of the eyes. The rate of posterior capsule rupture and vitreous loss was 0.6% (1/167; 95% confidence interval, 0%–1.8%). Ninety-five percent of eyes achieved a best-corrected visual acuity of at least 20/40. Conclusion When experienced surgeons could anticipate IFIS and employ compensatory surgical techniques, the complication rate from cataract surgery was low and the visual outcomes were excellent in eyes of patients with a history of tamsulosin use.
- Subjects :
- Atropine
Male
Tamsulosin
medicine.medical_specialty
Visual acuity
genetic structures
Medication history
medicine.medical_treatment
Eye disease
Visual Acuity
Intraoperative floppy iris syndrome
Postoperative Complications
Lens Implantation, Intraocular
medicine
Humans
Prospective Studies
Prospective cohort study
Intraoperative Complications
Adrenergic alpha-Antagonists
Sulfonamides
Phacoemulsification
Eye Color
business.industry
Incidence
Syndrome
Cataract surgery
medicine.disease
eye diseases
Surgery
Ophthalmology
Treatment Outcome
Iris Diseases
Anesthesia
Adrenergic alpha-1 Receptor Antagonists
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 15494713
- Volume :
- 114
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Ophthalmology
- Accession number :
- edsair.doi.dedup.....06f3ddbe23948b4e14ba4c89237f23d5