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CT, MRI and PET/CT features of abdominal manifestations of cutaneous melanoma: a review of current concepts in the era of tumor-specific therapies
- Source :
- Abdominal radiology (New York). 46(5)
- Publication Year :
- 2020
-
Abstract
- Abdominal manifestations in patients with cutaneous melanoma include involvement due to metastatic spread and immune checkpoint inhibitor induced adverse events. The purpose of this review is to provide a critical overview of abdominal manifestations in patients with cutaneous melanoma and highlight the current imaging challenges in the era of tumor-specific therapies. Immune checkpoint inhibitors represent a treatment with demonstrated efficacy in the treatment of advanced cutaneous melanoma but are associated with several abdominal adverse events that must be recognized. CT has a role in the identification of colitis, enteritis and pancreatitis, whereas MRI has an important role in the diagnosis of autoimmune pancreatitis. Current evidence demonstrates that MRI should be the preferred imaging technique for the detection and characterization of hepatic and splenic metastases from cutaneous melanoma. The role of 18F-FDG-PET/CT should be further evaluated but current literature suggests an efficacy in the detection of pancreatic metastases not seen on CT and MRI.
- Subjects :
- medicine.medical_specialty
Skin Neoplasms
Urology
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Fluorodeoxyglucose F18
Internal medicine
Positron Emission Tomography Computed Tomography
medicine
Humans
Radiology, Nuclear Medicine and imaging
Colitis
Adverse effect
Melanoma
Autoimmune pancreatitis
PET-CT
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
Gastroenterology
Magnetic resonance imaging
Hepatology
medicine.disease
Magnetic Resonance Imaging
030220 oncology & carcinogenesis
Positron-Emission Tomography
Cutaneous melanoma
Pancreatitis
Radiology
Radiopharmaceuticals
business
Tomography, X-Ray Computed
Subjects
Details
- ISSN :
- 23660058
- Volume :
- 46
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Abdominal radiology (New York)
- Accession number :
- edsair.doi.dedup.....06c8d11607462bfa6842e7426178ad73