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Supplementary Methods from Gemcitabine and CHK1 Inhibition Potentiate EGFR-Directed Radioimmunotherapy against Pancreatic Ductal Adenocarcinoma

Authors :
Kum Kum Khanna
Michael P. Brown
Sean M. Grimmond
Andrew V. Biankin
Angela Chou
Adnan M. Nagrial
Mariska Miranda
Murugan Kalimutho
Wei Shi
Marina Pajic
Fares Al-Ejeh
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Detailed methods of: EGFR immunohistochemistry of PDAC tissue microarrays Patient derived xenografts (PDXs) and cell lines (PDCLs) generation Cell culture Treatments in vitro Histological and immunoblotting analyses of PDXs post-treatment

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....068e1be2ab60f21de2276f4e8dafcf54
Full Text :
https://doi.org/10.1158/1078-0432.22456760