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An immunochemical focus assay to quantify replication competent and defective viruses involved in murine acquired immunodeficiency syndrome

Authors :
Tang Y
Ambros W. Hügin
Source :
Journal of virological methods. 77(2)
Publication Year :
1999

Abstract

Murine acquired immunodeficiency syndrome is a lymphoproliferative disease with a concurrently developing immunodeficiency. The disease is induced after injection of supernatant of a chronically infected cell line that releases a mixture of two replication competent virus classes and a replication incompetent virus species responsible for pathogenicity. An immunochemical detection assay for virus infected foci on cell monolayers has been developed. This assay allows quantification of all three types of virus.

Details

ISSN :
01660934
Volume :
77
Issue :
2
Database :
OpenAIRE
Journal :
Journal of virological methods
Accession number :
edsair.doi.dedup.....063633acc25e80ba0f25f9b9a7c76c3c