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Supplementary Data from ERK-Mediated Loss of miR-199a-3p and Induction of EGR1 Act as a 'Toggle Switch' of GBM Cell Dedifferentiation into NANOG- and OCT4-Positive Cells

Authors :
Thierry Virolle
Fanny Burel-Vandenbos
Patrick Verrando
Marie-Pierre Junier
Herve Chneiweiss
Philippe Paquis
Denys Fontaine
Laurence Bianchini
Beatrice Polo
Elisabet Gjernes
Sarah Elkeurti
David Nicolas Debruyne
Nathalie Sakakini
Laurent Turchi
Fabien Almairac
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

The supplemental figure 12 describes EGR1 expression during cell dedifferentiation. The supplemental figure 13 descries miR-199a-3p conserved sites in EGR1 3'UTR. The supplemental figure 14 describes the effects of shEGR1 and synthetic miR-199a-3p on EGR1 and miR-199a-3p expression and the consequence on NANOG expression.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....05f0bcd7ac153dd36a0b8fb9b634fed0
Full Text :
https://doi.org/10.1158/0008-5472.22425120.v1