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Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer
- Source :
- International journal of oncology. 39(6)
- Publication Year :
- 2011
-
Abstract
- The prognosis of unresectable advanced gastric cancer has improved over the last decade due to advances in chemotherapy. However, molecular targeting in gastric cancer therapy has been poorly established and the 5‑year survival rate is still
- Subjects :
- Male
Cancer Research
MAP Kinase Kinase 4
medicine.medical_treatment
Mice, Nude
Antineoplastic Agents
Apoptosis
Biology
Pharmacology
Bortezomib
Mice
Stomach Neoplasms
hemic and lymphatic diseases
medicine
Animals
Humans
Protease Inhibitors
Multiple myeloma
Cell Proliferation
Chemotherapy
Mice, Inbred BALB C
Hepatology
Oncogene
business.industry
Gastroenterology
NF-kappa B
Cancer
Cell cycle
medicine.disease
Boronic Acids
Xenograft Model Antitumor Assays
Oncology
Proteasome
Pyrazines
Cancer cell
Cancer research
Proteasome inhibitor
business
Reactive Oxygen Species
Proteasome Inhibitors
medicine.drug
Signal Transduction
Subjects
Details
- ISSN :
- 17912423
- Volume :
- 39
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- International journal of oncology
- Accession number :
- edsair.doi.dedup.....05c2ea6b306251e4c9ae0d3a90dc3daf