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Neuromyelitis optica in patients with increased interferon alpha concentrations

Authors :: Jac Williams
Sarah McGlasson
Sarosh Irani
Darragh Duffy
Yanick Crow
David Hunt
Katy Murray
Robert Wilson
Andrew P Jackson
Alexa Jury
Mathieu Rodero
Vincent Bondet
Anu Jacob
Shahd Hamid
Nuno Cordeiro
Ondrej Dolezal
Patrick Statham
Stewart Wiseman
Joanna Wardlaw
Christina Hertel
Adrian Hayday
Anne Rowling Clinic [Edinburgh, UK]
University of Edinburgh
Medical Research Council Institute of Genetics and Molecular Medicine [Edinburgh, UK]
Oxford Autoimmune Neurology Group [Oxford, UK]
University of Oxford
Immunobiologie des Cellules dendritiques
Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)
DH is supported by the Wellcome Trust (215621/Z/19/Z) and the Medical Research Foundation. YC is supported by an European Research Council advanced grant (786142-E-T1IFNs). YC and DH are supported by Connect Immune research (Multiple Sclerosis Society, Juvenile Diabetes Research Foundation, Versus Arthritis). AJ is supported by the UK Medical Research Council. SRI is supported by the Wellcome Trust (104079/Z/14/Z), the British Medical Association's Vera Down (2013) and Margaret Temple (2017) grants, and Epilepsy Research UK (P1201). The research was funded by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre.
We thank the Uppsala Monitoring Centre (Uppsala, Sweden) and the UK Medicines and Healthcare products Regulatory Agency for providing spontaneous reporting data. We thank our patients for willingness and consent to report these cases. Patients 1, 3, and 4 were enrolled in clinical studies approved by: Leeds (East) Research Ethics Committee (10/H1307/132
patient 3) and South-East Scotland Research Ethics Committee 01 (14/SS/0003
patients 1 and 4). The Scottish Neuromyelitis Optica Spectrum Disorder Clinic is part of the NHS NMO UK specialised service.
Scottish NMOSD study group : Murray K, Wilson R, Jackson AP, Jury A, Rodero M, Bondet V, Jacob A, Hamid S, Cordeiro N, Dolezal O, Statham P, Wiseman S, Wardlaw J, Hertel C, Hayday A.
Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601)
Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)
University of Oxford [Oxford]
Immunologie Translationnelle - Translational Immunology
Institut Pasteur [Paris]
Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163)
Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)
Dept Neurology, Western General Hospital
Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]
Imagine - Institut des maladies génétiques (IMAGINE - U1163)
Vougny, Marie-Christine
Source :: Williams, J, Mcglasson, S, Irani, S, Duffy, D, Crow, Y, Hunt, D, Katy, M, Robert, W, Andrew P, J, Alexa, J, Mathieu, R, Vincent, B, Anu, J, Shahd, H, Nuno, C, Ondrej, D, Patrick, S, Stewart, W, Joanna, W, Christina, H & Adrian, H 2020, ' Neuromyelitis optica in patients with increased interferon alpha concentrations ', The Lancet Neurology, vol. 19, no. 1, pp. 31-33 . https://doi.org/10.1016/S1474-4422(19)30445-4, The Lancet Neurology, The Lancet Neurology, 2020, 19 (1), pp.31-33. ⟨10.1016/S1474-4422(19)30445-4⟩, The Lancet Neurology, Elsevier, 2020, 19 (1), pp.31-33. ⟨10.1016/S1474-4422(19)30445-4⟩
Publication Year :: 2020
Abstract: International audience; Recombinant interferon alpha is used to treat several immunological, oncological, and infectious diseases,1 and various serious side-effects have been associated with its therapeutic use. We want to bring attention to the development of neuromyelitis optica spectrum disorder (NMOSD) [...]

Details

Language :: English
ISSN :: 14744422 and 14744465
Database :: OpenAIRE
Journal :: Williams, J, Mcglasson, S, Irani, S, Duffy, D, Crow, Y, Hunt, D, Katy, M, Robert, W, Andrew P, J, Alexa, J, Mathieu, R, Vincent, B, Anu, J, Shahd, H, Nuno, C, Ondrej, D, Patrick, S, Stewart, W, Joanna, W, Christina, H & Adrian, H 2020, ' Neuromyelitis optica in patients with increased interferon alpha concentrations ', The Lancet Neurology, vol. 19, no. 1, pp. 31-33 . https://doi.org/10.1016/S1474-4422(19)30445-4, The Lancet Neurology, The Lancet Neurology, 2020, 19 (1), pp.31-33. ⟨10.1016/S1474-4422(19)30445-4⟩, The Lancet Neurology, Elsevier, 2020, 19 (1), pp.31-33. ⟨10.1016/S1474-4422(19)30445-4⟩
Accession number :: edsair.doi.dedup.....05c07fc363711f2e459d3cb2e6be90e2
Full Text :: https://doi.org/10.1016/S1474-4422(19)30445-4