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A recommended treatment algorithm in relapsing multiple sclerosis: report of an international consensus meeting
- Source :
- European Journal of Neurology. 13:61-71
- Publication Year :
- 2006
- Publisher :
- Wiley, 2006.
-
Abstract
- An International Working Group for Treatment Optimization in MS met to recommend evidence-based therapeutic options for the management of suboptimal responses or intolerable side-effects in patients treated with disease-modifying drugs (DMDs) for multiple sclerosis (MS). Several DMDs are now available for the treatment of MS that have been shown to alter the clinical course of the disease by decreasing disease activity and delaying the progression of disability. Nevertheless, many patients continue to experience disease activity whilst on treatment, and recommendations have been made on how the success of therapy in an individual patient can be assessed. However, even after having identified criteria for a suboptimal response to current treatments, clinicians require guidance on how to improve the outcomes. This report summarizes the conclusions from a workshop at which this issue was addressed. We suggest treatment pathways for optimizing therapy for those patients with suboptimal responses to DMDs, and therapeutic options for patients with unacceptable side-effects on their current therapy.
- Subjects :
- medicine.medical_specialty
Evidence-Based Medicine
Interferon beta
business.industry
Multiple sclerosis
Clinical course
Disease Management
Disease
International working group
medicine.disease
Disease activity
Multiple Sclerosis, Relapsing-Remitting
Neurology
medicine
Physical therapy
Humans
In patient
Neurology (clinical)
Glatiramer acetate
Intensive care medicine
business
Algorithms
medicine.drug
Subjects
Details
- ISSN :
- 14681331 and 13515101
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- European Journal of Neurology
- Accession number :
- edsair.doi.dedup.....05b05d2f5f26fb031b8fe1a27fa18958
- Full Text :
- https://doi.org/10.1111/j.1468-1331.2006.01147.x